Composition

Turmix Tablets

Each film coated tablet contains:
Curcumin (95% standardized)	300mg
Piperine (95% standardized)	5mg

Mechanism of Action

Curcumin

• Anti-Inflammatory
  Research shows Curcumin is highly pleiotropic molecule capable of interacting with numerous molecular targets involved in inflammation. Curcumin modulates the inflammatory response by down-regulating the activity of Cyclooxygenase-2 (COX-2), Lipoxygenase, and inducible Nitric Oxide Synthase (iNOS) enzymes; inhibits the production of the inflammatory Cytokines- Tumor Necrosis Factor-alpha (TNF-a), interleukin (IL) -1, -2, -6, -8, and -12.

• Anti-Oxidant
  Curcumin is a potent scavenger of reactive oxygen species (ROS) including Superoxide anion, Nitric oxide & Hydroxyl radicals. In various clinical studies, it has been shown that Curcumin increases levels of vitamin C & E in saliva & prevents lipid peroxidation & DNA damage.

• DNA Protecting
  Curcumin inhibits NF-KB & various other chemical mediators responsible for DNA damage & disease progression. Curcumin is also found to protect DNA by preventing interaction of DNA with various Carcinogens.

• Anti Fibrotic
  Curcumin inhibits proliferation of fibroblasts and myofibroblasts; it also disturbs the cell cycle, induces apoptosis and decreases the generation of collagen type I and III in myofibroblasts.

• Anti-Carcinogenic
  Curcumin exerts clinically relevant anti-cancer effects & opens up a new avenue for chemoprevention & treatment of Oral, Skin, Colorectal, Breast & other types of cancers. Curcumin induces apoptosis, inhibits cell cycle progression, invasion & metastatis by blocking NF-KB & other molecular factors.

• Immunomodulator
  Curcumin shows potent immunomodulatory action that can modulates the activation of T cells, B cells, Macrophages, Neutrophils, Natural killer cells, and Dendritic cells. Curcumin can also downregulate the expression of various pro-inflammatory Cytokines including TNF, Interleukins and Chemokines. Interestingly, Curcumin can also enhance antibody responses.

Piperine: Nature's Best Bioavailability Enhancer

1. Inhibits hepatic & intestinal glucuronidation of Curcumin
2. Increases bioavailability of Curcumin by 2000% in humans with no adverse effects

• Pre-cancerous lesions
  • Sub-mucous fibrosis,
  • Oral Leukoplakia
  • Lichen planus
• Other oral lesions: Gingivitis / Periodontitis / stomatitis
• Cancer (Oral / Lung / Head & Neck / Prostate / Cervical Cancer etc.)
• Rheumatoid Arthritis / Osteoarthritis
• Skin disorders (Psoriasis / Eczema)
• Cough / Cold /Bronchitis
• Liver Problems / IBS
• Adjuvant Therapy in Malaria

 

• Optimization and characterization of transdermal film of curcumin containing natural oils as permeation enhancer by response surface methodology.

• Efficacy of Turmeric in Reducing Burning Sensation in Oral Submucous Fibrosis: An Observational Study

• Nanoemulsion Based Concomitant Delivery of Curcumin and Etoposide: Impact on Cross Talk Between Prostate Cancer Cells and Osteoblast During Metastasis

• Preparation and Evaluation of Curcumin Invasomes