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Post Menopausal Osteoporosis

Cessation of menstruation is menopause. It is a genetically programmed arrest of ovarian function.

Around 50 years, a woman's body starts to change. After a long career of producing eggs and estrogen, the ovaries take an early retirement and the body goes through the hormone withdrawal process - menopause. The average age of menopause is 51 years old, although this varies. At menopause a woman's level of estrogen and progesterone, hormones that cause menstruation, decrease and thus menstruation ceases.

After menopause (post menopause) there is an increased risk of osteoporosis because estrogen hormone depletes. Although all women are affected by menopause, some women don't experience menopausal symptoms, while others benefit from the medical treatment of the symptoms.


Each film-coated tablet contains:
Ipriflavone 300mg
Alfacalcidol 0.25mcg
Calcium Carbonate 500mg
(eq. to 200mg elemental calcium)


Synthetic Derivative of Naturally Occurring Soya Isoflavones

Mechanism of action

Inhibitors of Bone Resorption

Ipriflavones inhibit bone breakdown by formation of new osteoclasts & activation of mature osteoclasts.

Lack of Estrogen Effct (Non-Estrogen / Non-Hormonal

Ipriflavones mimic the action of estrogen but are non-estrogenic in nature. Action not mediated by direct interaction with estrogen receptors Ipriflavone specific binding sites -Selective effect on bone and not reproductive tissue

Alfacalcidol Vitamin D

Vitamin D is one of the most important regulators of calcium. It is essential for enhancing calcium absorption in the intestine and decreasing the excretion of calcium in the kidneys.
Treating Vitamin D deficiency with supplements can significantly reduce the number of hip fractures in people with osteoporosis. Studies have also shown that ipriflavone in conjunction with Vitamin D can help reduce post menopausal bone loss better than either of these two substances alone.

Safety Issues

Nearly 3,000 people have used ipriflavone in clinical studies, with no more side effects than those taking placebo.


  • Peri and Post menopausal osteoporosis.
  • Senile osteoporpsis.
  • Drug induced osteoporosis.


One tablet one or two times a day.

MRP / Packaging

MRP: Rs.1090
Strip Packaging: One strip contains 10 tablets. 10 strips in a box

Target Audience

  • Gynecologists.
  • Physicians.
  • Orthopedicians.


  • Promote bone formation.
  • Inhibit osteoclastic activity.
  • Non Hormonal/non-esterogenic.


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